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Monitor Carefully (1)modafinil will raise the amount or impact of citalopram by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Citalopram twenty mg/day is the utmost advised dose for people using CYP2C19 inhibitors due to chance of QT prolongation.Watch Intently (one)istradefylline will enhance the amount or effect of modafinil